Clinical and Electron Microscopic Investigation for Three Cases with Acute Myelomegakaryocytic Leukemia

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  • Acute Myelomegakaryoblastic Leukemia 3例の臨床的および電顕細胞学的考察
  • Acute Myelomegakaryoblastic Leukemia3レイ

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Description

Developement of monoclonal antibodies and electron microscopic cytochemistry has made it possible to identify megakaryoblast. On the name of “megakaryocytic leukemia”, many case reports has been discussed. We experimented three cases with acute leukemia in which both megakaryoblast and myeloblast proliferated. Clinical course was placed to be uniformly specific that the percentage of leukemic cells was low, but these diseases's onset was slow and gradual. We stressed that these disorders was a new disease entity, called “Myelomegakaryocytic Leukemia”. Myelomegakaryocytic leukemia is suspected to be an acute leukemia with the simultaneous growth of two leukemic clones, originated from same stem cells, but is never considered to be mixed leukemia.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 28 (6), 857-864, 1987

    The Japanese Society of Hematology

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