Plasmacytoma with multiple hypervascular lesions revealed by angiography in a patient with multiple myeloma

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  • HANDA Hiroshi
    School of Health Science, Faculty of Medicine, Gunma University Department of Internal Medicine, Ashikaga Red Cross Hospital
  • IRISAWA Hiroyuki
    Department of Internal Medicine, Ashikaga Red Cross Hospital Department of Medicine and Clinical Science, Graduate School of Medicine, Gunma University
  • KOMATSUMOTO Satoru
    Department of Internal Medicine, Ashikaga Red Cross Hospital
  • MATSUSHIMA Takafumi
    Department of Medicine and Clinical Science, Graduate School of Medicine, Gunma University
  • TSUKAMOTO Norifumi
    Department of Medicine and Clinical Science, Graduate School of Medicine, Gunma University
  • NOJIMA Yoshihisa
    Department of Medicine and Clinical Science, Graduate School of Medicine, Gunma University
  • MURAKAMI Hirokazu
    School of Health Science, Faculty of Medicine, Gunma University

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Other Title
  • 血管造影にてmultiple hypervascular lesionを呈した形質細胞腫を伴う多発性骨髄腫
  • 症例報告 血管造影にてmultiple hypervascular lesionを呈した形質細胞腫を伴う多発性骨髄腫
  • ショウレイ ホウコク ケッカンゾウエイ ニテ multiple hypervascular lesion オ テイシタ ケイシツ サイボウ シュ オ トモナウ タハツセイ コツズイシュ

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Abstract

A 68-year-old woman suffering from a left iliac tumor and severe back pain was admitted to another hospital in May 1999. The bone X-ray, CT scan and MRI demonstrated a 7 cm×5 cm left iliac tumor with osteolysis and she was transferred to our hospital. Angiography demonstrated multiple hypervascular lesions in the left ilium, lumbar vertebrae, left ischium, left pubis and left rib. The tumor was resected and diagnosed as a plasmacytoma. Immunoelectrophoresis did not show any M-protein in the serum and urine, but the patient was diagnosed as having a non-secretory or low producing multiple myeloma because of the presence of 42.8% of abnormal plasma cells in the bone marrow aspirate. Her symptoms improved following 3 courses of MCNU-VMP therapy and the bone marrow plasma cells decreased to less than 5%. She was discharged and treated as an outpatient but relapsed and died of chemotherapy-resistant myeloma. We report this case because macro-angiogenesis in a multiple myeloma demonstrated by angiography is rare and interesting.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 47 (6), 521-525, 2006

    The Japanese Society of Hematology

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