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Acute promyelocytic leukemia with a history of RAEB in transformation and the 15/17 translocation.
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- OGAWA Kazuei
- The First Department of Internal Medicine, Fukushima Medical College
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- SHINEHA Haruko
- The First Department of Internal Medicine, Fukushima Medical College
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- ABE Rokuo
- The First Department of Internal Medicine, Fukushima Medical College
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- SHICHISHIMA Tsutomu
- The First Department of Internal Medicine, Fukushima Medical College
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- KIMURA Hideo
- The First Department of Internal Medicine, Fukushima Medical College
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- YUI Tokuo
- The First Department of Internal Medicine, Fukushima Medical College
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- KAWAGUCHI Michiko
- The First Department of Internal Medicine, Fukushima Medical College
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- MATSUDA Shin
- The First Department of Internal Medicine, Fukushima Medical College
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- UCHIDA Tatsumi
- The First Department of Internal Medicine, Fukushima Medical College
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- KARIYONE Shigeo
- The First Department of Internal Medicine, Fukushima Medical College
Bibliographic Information
- Other Title
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- RAEB in transformationの時期を経て発症した急性前骨髄球性白血病
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Description
A 34-year old female was admitted to our clinic because of fever and general fatigue on March 26, 1987. On admission, peripheral blood (PB) revealed pancytopenia. Bone marrow smears revealed 9.0% of promyelocytic cells with or without Auer rods. Diagnosis of RAEB in transformation was made. Chromosome study of the bone marrow cells showed t(15;17) in 3 out of 20 cells analysed. After 3 months, the leukemic cells were observed in PB and increased in number. Then the patient showed bleeding tendency and fibrin degradation products (FDP) increased up to 40 μg/ml. And the leukemic cells were over 30% in PB at the end of July, 1987. The diagnosis of APL with DIC was made.<br>To our knowledge, this is the first case of APL with a history of MDS with t(15;17).
Journal
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- Rinsho Ketsueki
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Rinsho Ketsueki 30 (1), 67-71, 1989
The Japanese Society of Hematology
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Keywords
Details 詳細情報について
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- CRID
- 1390282680010871424
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- NII Article ID
- 130004918819
- 10007321654
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- COI
- 1:STN:280:BiaB3snntFQ%3D
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- ISSN
- 18820824
- 04851439
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- PubMed
- 2716201
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- Text Lang
- ja
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- Article Type
- journal article
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- Data Source
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- JaLC
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed