Red Cell Distribution Width in Iron Deficiency Anemia

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  • 鉄欠乏性貧血における赤血球粒度分布幅
  • テツ ケツボウセイ ヒンケツ ニ オケル セッケッキュウ リュウドブン ヌノハ

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Abstract

Red cell volume distribution width as a mean for diagnosing iron deficiency by using Sysmex E-4000 and Coulder S-plus STKR was examined. RDW by S-plus STKR and RDW-CV by E-4000 showed larger values concomitant with the development of iron deficiency. More than 80% of iron deficiency anemia and 50% of iron deficiency could be screened by red cell distribution width without serum iron or ferritin measurements. All 14 patients with iron deficiency anemia had a single, microcytic population of red cells before treatment. In 12 of 14 patients, a new population was of normal size after the administration of iron. In 2 of 14, the new population was macrocytic. In a patient with megaloblastic anemia and 4 with polycythemia vera, red cell distribution curves were also taken during the treatment. RDW-CV had larger values due to relative iron deficiency associated with hypoferremia. It was discussed that red cell distribution width was clinically useful in the diagnosis of iron deficiency status and iron deficiency anemia.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 29 (6), 802-806, 1988

    The Japanese Society of Hematology

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