Is an oral disintegrating tablets a formulation that is easy to ingest for patients experiencing difficulty with eating and swallowing?

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  • Umaki Yoshifumi
    Department of Neurology, National Hospital Organization Tokushima Hospital
  • Nozaki Sonoko
    School of Rehabilitation, Department of Physical Therapy, Hyogo University of Health Sciences
  • Sugishita Shuhei
    Department of Rehabilitation, Takasago Municipal Hospital
  • Shiimoto Kumiko
    Department of Rehabilitation, National Hospital Organization Tokushima Hospital
  • Hashiguchi Shuji
    Department of Neurology, National Hospital Organization Tokushima Hospital
  • Inui Toshio
    Department of Neurology, National Hospital Organization Tokushima Hospital
  • Adachi Katsuhito
    Department of Internal Medicine, National Hospital Organization Tokushima Hospital

Bibliographic Information

Other Title
  • 口腔内崩壊錠は摂食・嚥下障害患者にとって内服しやすい剤形か？
  • コウクウ ナイ ホウカイジョウ ワ セッショク エンカ ショウガイ カンジャ ニ トッテ ナイフク シヤスイ ザイケイ カ

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Description

Oral disintegrating tablets (hereafter, ODT) can be ingested without water. We conducted a videoscopic examination to determine whether they are also useful as internal agents for patients experiencing difficulty with eating and swallowing. Normal tablets and dummy preparations of ODT were orally administered to six patients with neurological diseases who were either diagnosed with or aware of difficulty in eating and swallowing, and observations were conducted using a videoscope. Two subjects were able to ingest both the normal tablet and the dummy preparation without any problem; two subjects were able to ingest the normal tablet without any problem but the dummy preparation remained in their pharynx; and two subjects had both the normal tablet and the dummy preparation remained in the pharynx. There was no feeling of residue in the four cases in which the dummy preparation remained in the pharynx. ODT is not necessarily easy to ingest for patients with neurological diseases who have difficulty eating and swallowing, and it was believed that repeated swallowing or alternate swallowing of a thick liquid is required for ingestion.<br>

Journal

  • Rinsho Shinkeigaku

    Rinsho Shinkeigaku 49 (2/3), 90-95, 2009

    Societas Neurologica Japonica

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