CD5陽性B細胞前リンパ球性白血病

書誌事項

タイトル別名
  • CD5-positive B-cell prolymphocytic leukemia
  • CD5 ヨウセイ B サイボウ ゼン リンパキュウセイ ハッケツビョウ

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説明

CD5 is a T-cell marker that is expressed in mature B cell malignancies and other B cell chronic lymphoproliferative disorders, but the biologic function of CD5 is unknown. We report a 68-year-old woman with B-cell prolymphocytic leukemia (B-PLL) expressing CD5 antigen. On admission, jaundice and hepatosplenomegaly were noted. Hematological examination demonstrated a platelet count of 2.8×104l and a white blood cell count of 19,900/μl with 69% PLL cells. Surface marker analysis of the PLL cells was positive for CD5, CD19, CD20, sIgM, and was negative for CD23, and cyclin D1 was negative in immunostaining.

収録刊行物

  • 臨床血液

    臨床血液 51 (1), 80-82, 2010

    一般社団法人 日本血液学会

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