A Case of Erythroleukemia with Sideroblastic Anemia

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  • HIRAI Hiroko
    Department of Hematology, Central Hospital of Japanese National Railways
  • YAMAGISI Atuko
    Department of Hematology, Central Hospital of Japanese National Railways
  • HAYAKAWA Kinya
    Department of Central Laboratory, Central Hospital of Japanese National Railways
  • YAMADA Kiyomi
    Division of Genetics, Clinical Research Institute, National Medical Center Hospital

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Other Title
  • 鉄芽球性貧血を伴う赤白血病の1例
  • テツガキュウセイ ヒンケツ オ トモナウ セキハッケツビョウ ノ 1レイ

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Abstract

A 26-year-old man. During the treatment on acute hepatitis, cystitis was complicated. After an administration of 5g of chloramphenicol and 8g of thiophenicol, he fell into pancytopenia and 16% of myeloblast was seen in the peripheral blood. However, no increase in myeloblasts was noted in the bone marrow. Anemia was improved when the drugs were discontinued, but thrombocytopenia persisted and a few myeloblasts were seen in the peripheral blood. He fell into severe anemia 6 months after the administration of chloramphenicol. He developed erythroleukemia with sideroblastic anemia. He became better for a moment after the administration of adrenocortical steroids, but he suffered from pneumonia at the end stage and died about 23 months after the occurrence of pancytopenia or 17 months after the occurrence of erythroleukemia. The authors reported this case with reference of the literature.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 20 (12), 1610-1618, 1979

    The Japanese Society of Hematology

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