Hodgkin病に合併したSecondary amyloidosisの一症例

DOI Web Site PubMed

書誌事項

タイトル別名
  • A Case of Hodgkin's Disease Associated with Amyloidosis
  • Hodgkin病に合併したSecondary amyloidosisの1症例
  • Hodgkinビョウ ニ ガッペイシタ Secondary amyloidos

この論文をさがす

抄録

A 55-year-old male was admitted to our hospital with lymphadenopathy and high fever in January, 1978. Lymphocytic predominant type of Hodgkin's disease was revealed by the biopsy. He was treated with 4 times of combination chemotherapy, VEMP, and next 4 times treated with VENP. OK-432 has been added on the therapy since March. After these therapy, lymphadenopathy disappered except for 2 lymph nodes of left neck. As localy treatment, 5 or 10 KE of OK-432 were injected into these two lymph nodes. Two weeks later, by the biopsy, amyloidosis was revealed with a few of Hodgkin cells in these lymph nodes treated with OK-432. However, histologicaly same findings were observed in axillar and inguinal lymph nodes. Moreover, amyloid deposit was revealed in rectal muscle, but not in liver tissue. After the treatment of more 4 times of VENP, all lymphadenopathy disappeared.<br>Several causes are suspected to explain amyloidosis in this case as follows:<br>1) The same immunological abnormality which is suspected to induce Hodgkin's disease.<br>2) Reduced immune response with Hodgkin's disease and/or following combination chemotherapy.<br>3) Side effect of OK-432.

収録刊行物

  • 臨床血液

    臨床血液 20 (11), 1505-1511, 1979

    一般社団法人 日本血液学会

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ