A Case of Bence Jones Protein Kappa Type Myeloma with Adult Fanconi syndrome

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  • HIRAI Hiroshi
    First Department of Internal Medicine, Nihon University School of Medicine
  • SHIDA Mitumasa
    First Department of Internal Medicine, Nihon University School of Medicine
  • IGEI Iwao
    First Department of Internal Medicine, Nihon University School of Medicine
  • NISHINARITA Susumu
    First Department of Internal Medicine, Nihon University School of Medicine
  • TAKAHASHI Koichi
    First Department of Internal Medicine, Nihon University School of Medicine
  • TAKEUCHI Jin
    First Department of Internal Medicine, Nihon University School of Medicine
  • BABA Masumi
    First Department of Internal Medicine, Nihon University School of Medicine
  • KIKUOKA Masakazu
    First Department of Internal Medicine, Nihon University School of Medicine
  • TAKEO Hiroshi
    First Department of Internal Medicine, Nihon University School of Medicine
  • TONO Hiroya
    First Department of Internal Medicine, Nihon University School of Medicine
  • TAKESHITA Tokuzo
    First Department of Internal Medicine, Nihon University School of Medicine
  • AMEMIYA Yoichi
    First Department of Internal Medicine, Nihon University School of Medicine
  • MORITA Koichi
    First Department of Internal Medicine, Nihon University School of Medicine
  • HAYASHI Hiroto
    First Department of Internal Medicine, Nihon University School of Medicine
  • AMAKI Ichita
    First Department of Internal Medicine, Nihon University School of Medicine

Bibliographic Information

Other Title
  • 成人型Fanconi症候群を呈したBence Jones κ型骨髄腫の1例
  • セイヒトガタ Fanconi ショウコウグン オ テイシタ Bence Jon

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Abstract

Recently we experienced adult Fanconi syndrome seemed as being secondary to Bence Jones protein kappa type myeloma.<br>The patient was a thirty-one year old man who had had glycosuria and proteinuria since about seven years. In the bone marrow were observed myeloma cells containing needle-shaped cytoplasmic inclusion bodies. Bence Jones protein kappa type was detected by urine protein immunoelectrophoresis. Kidney biopsy specimen showed remarkable deposition of protein-like bodies in proximal tubules.<br>In the future, the presence of plasma cell dyscrasia should be taken into consideration in patients with adult Fanconi syndrome.<br>However, monoclonal increase of immunoglobulin is rare in this type of myeloma, therefore, it appears necessary to detect Bence Jones protein thoroughly by such means as urine protein immunoelectrophoresis.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 19 (3), 234-239, 1978

    The Japanese Society of Hematology

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