Case of posterior reversible encephalopathy syndrome due to azathioprine
-
- Ogawa Ryo
- Department of Neurology, South Miyagi Medical Center Department of Neurology, Tohoku University Hospital
-
- Oikawa Takanori
- Department of Neurology, South Miyagi Medical Center
-
- Shijo Tomomi
- Department of Neurology, South Miyagi Medical Center Department of Neurology, Tohoku University Hospital
-
- Kanno Shigenori
- Department of Neurology, South Miyagi Medical Center
-
- Shibuya Satoshi
- Department of Neurology, South Miyagi Medical Center
-
- Mochizuki Hiroshi
- Department of Neurology, South Miyagi Medical Center
Bibliographic Information
- Other Title
-
- アザチオプリン内服によりposterior reversible encephalopathy syndromeを発症した1例
Search this article
Abstract
This report describes a 15-year-old woman presenting posterior reversible encephalopathy syndrome (PRES) due to azathioprine. She was under treatment for ulcerative colitis. She was prescribed azathioprine seven days before admission. Four days after, she complained of headache. Then, she disturbed consciousness and showed generalized convulsive seizure on the day of admission. Magnetic resonance imaging (MRI) revealed vasogenic edema in both hemispheres. She was discontinued azathioprine and treated by anticonvulsant. Her symptoms were recovered and the MRI findings were disappeared. We diagnosed as PRES due to azathioprine because of clinical course and MRI findings. Only one case of PRES due to azathioprine is reported previously. Our case is the first report that showed the changes and improvement of MRI findings along the clinical course.
Journal
-
- Rinsho Shinkeigaku
-
Rinsho Shinkeigaku 55 (12), 936-939, 2015
Societas Neurologica Japonica