Gliomatosis cerebri with multifocal progressive lesions on MRI

DOI Web Site 18 References
  • Sakushima Ken
    Department of Neurology, Hokkaido University Graduate School of Medicine
  • Yashima-Yamada Moemi
    Department of Neurology, Hokkaido University Graduate School of Medicine
  • Kubota Kanako
    Department of Surgical Pathology, Hokkaido University Hospital
  • Sawamura Yutaka
    Department of Neurosurgery, Hokkaido University Graduate School of Medicine
  • Yabe Ichiro
    Department of Neurology, Hokkaido University Graduate School of Medicine
  • Sasaki Hidenao
    Department of Neurology, Hokkaido University Graduate School of Medicine

Bibliographic Information

Other Title
  • 画像的に多巣性の進展経過を示した大脳膠腫症の１例
  • ガゾウテキ ニ タソウセイ ノ シンテン ケイカ オ シメシタ ダイノウコウシュショウ ノ 1レイ

Search this article

Abstract

A 77-year-old woman with cognitive impairment and multifocal progressive lesions on brain MRI was admitted to our hospital. Analysis of blood and cerebrospinal fluid showed no evidence of infection, autoimmune disease, or metabolic abnormalities. Histological examination of biopsied tissue from a lesion in the right frontal lobe revealed an abnormally increased glial cell density with enlarged nuclei and a high MIB-1 index. These pathological findings coupled with her progressive clinical history indicated a diagnosis of gliomatosis cerebri. General characteristics of gliomatosis cerebri include diffuse infiltrative lesions in neuroimaging with or without mass effect. However, the present case showed unusual multifocal manifestations in brain MRI. Therefore, histopathological examination must be taken into account for a proper diagnosis.<br>

Journal

  • Rinsho Shinkeigaku

    Rinsho Shinkeigaku 51 (2), 145-148, 2011

    Societas Neurologica Japonica

References(18)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top