Acute exacerbation of organizing pneumonia leading to sudden death in a patient with sarcoidosis-lymphoma syndrome
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- IIZUKA Kazuhide
- Department of Hematology, Juntendo University School of Medicine Department of Next Generation Hematological Laboratory Medicine, Juntendo University School of Medicine
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- ANDO Jun
- Department of Hematology, Juntendo University School of Medicine
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- MASUDA Azuchi
- Department of Hematology, Juntendo University School of Medicine
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- OCHIAI Tomonori
- Department of Hematology, Juntendo University School of Medicine
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- TOMOMASA Ran
- Department of Human Pathology, Juntendo University, School of Medicine
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- YASUDA Hajime
- Department of Hematology, Juntendo University School of Medicine
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- TAKAKU Tomoiku
- Department of Hematology, Juntendo University School of Medicine
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- OTA Yasunori
- Department of Diagnostic Pathology, Research Hospital, The Institute of Medical Science, The University of Tokyo
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- YAO Takashi
- Department of Human Pathology, Juntendo University, School of Medicine
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- GOTOH Akihiko
- Department of Hematology, Juntendo University School of Medicine
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- KOMATSU Norio
- Department of Hematology, Juntendo University School of Medicine
Bibliographic Information
- Other Title
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- 器質化肺炎の急性増悪を合併し突然死に至ったsarcoidosis-lymphoma syndrome
- 症例報告 第3回日本血液学会関東甲信越地方会 優秀演題 器質化肺炎の急性増悪を合併し突然死に至ったsarcoidosis-lymphoma syndrome
- ショウレイ ホウコク ダイ3カイ ニホン ケツエキ ガッカイ カントウ コウシンエツチホウカイ ユウシュウ エンダイ キシツカ ハイエン ノ キュウセイ ゾウアク オ ガッペイ シ トツゼンシ ニ イタッタ sarcoidosis-lymphoma syndrome
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Abstract
<p>The subject was an 83-year-old female; she had a history of Propionibacterium acnes-related sarcoidosis at the age of 79 years. At diagnosis, she was treated with clarithromycin and achieved remission. Four years later, during a routine physical check-up, she presented with pulmonary opacities and swelling of multiple lymph nodes. A definitive diagnosis of lymphoma could not be made by inguinal lymph node biopsy. The patient’s general condition was good, and we observed her clinical course. Oh the 56th day of her illness, she died suddenly. Autopsy revealed diffuse large B-cell lymphoma (DLBCL). Sarcoidosis-lymphoma syndrome (SLS) was diagnosed after sampling hyalinized nodules from both lungs. The cause of death was organizing pneumonia around an epithelioid granuloma and cor pulmonale. Organization markedly increased around the DLBCL. These findings might be associated with cor pulmonale. Although SLS often appears during chronic active sarcoidosis, sudden death is rare and there are few reports on SLS in Japan. We report this case along with a review of the literature.</p>
Journal
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- Rinsho Ketsueki
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Rinsho Ketsueki 58 (8), 927-932, 2017
The Japanese Society of Hematology
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Keywords
Details 詳細情報について
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- CRID
- 1390282680013453184
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- NII Article ID
- 130006067979
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- NII Book ID
- AN00252940
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- ISSN
- 18820824
- 04851439
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- NDL BIB ID
- 028513999
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- PubMed
- 28883276
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed