Progressive cerebellar ataxia with euthyroid Hashimoto's disease -Implication of autoantibodies associated with Hashimoto's disease in progressive cerebellar ataxia-

DOI Web Site 2 Citations 52 References
  • Yabe Ichiro
    Department of Neurology, Hokkaido University Graduate School of Medicine
  • Sato Kazunori
    Department of Neurology, Hokkaido University Graduate School of Medicine
  • Soma Hiroyuki
    Department of Neurology, Hokkaido University Graduate School of Medicine
  • Sasaki Hidenao
    Department of Neurology, Hokkaido University Graduate School of Medicine

Bibliographic Information

Other Title
  • 甲状腺機能正常な″橋本病″にともなう進行性小脳性運動失調症の臨床的検討～小脳性運動失調における橋本病の自己抗体の関わりについて～
  • 甲状腺機能正常な"橋本病"にともなう進行性小脳性運動失調症の臨床的検討--小脳性運動失調における橋本病の自己抗体の関わりについて
  • コウジョウセン キノウ セイジョウナ ハシモトビョウ ニ トモナウ シンコウセイ ショウノウセイ ウンドウ シッチョウショウ ノ リンショウテキ ケントウ ショウノウセイ ウンドウ シッチョウ ニ オケル ハシモトビョウ ノ ジコ コウタイ ノ カカワリ ニ ツイテ

Search this article

Abstract

To determine the frequency of cerebellar ataxia patients with autoantibodies for Hashimoto's disease, we analyzed 68 patients who were examined serum test for autoantibodies of Hashimoto disease among 178 cerebellar ataxia patients who visited our neurology clinic from January 2005 until December 2007. In these 68 patients, 8 had autoantibodies for Hashimoto's disease. Five of these 8 patients were diagnosed with hereditary spinocerebellar ataxia by genetic analysis. Moreover, one patient was diagnosed with probable multiple system atrophy by neurological examination. Cerebellar ataxic disease of known causes was ruled out for the remaining two cases; they were euthyroid and their cerebellar ataxia was slowly progressive and were diagnosed with cortical cerebellar atrophy. Although Hashimoto's disease may associate with cerebellar ataxia because cortical cerebellar atrophy is a heterogeneous condition, this association is not clear at present.<br>

Journal

  • Rinsho Shinkeigaku

    Rinsho Shinkeigaku 48 (9), 640-645, 2008

    Societas Neurologica Japonica

Citations (2)*help

See more

References(52)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top