Three Cases of Acute Leukemia who Survive More Than Five Years

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  • NAKATSUJI Tadako
    Third Department of Internal Medicine, Yamaguchi University School of Medicine
  • MATSUMOTO Noboru
    Third Department of Internal Medicine, Yamaguchi University School of Medicine
  • ODA Susumu
    Third Department of Internal Medicine, Yamaguchi University School of Medicine
  • MIWA Shiro
    Third Department of Internal Medicine, Yamaguchi University School of Medicine

Bibliographic Information

Other Title
  • 5年以上生存している急性白血病の3例
  • 5ネン イジョウ セイゾンシテ イル キュウセイ ハッケツビョウ ノ 3レイ

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Description

Three patients with acute leukemia, who have survived five years or more after the initial remission, are reported. Patient 1 (a high school girl) was diagnosed as acute lymphoblastic leukemia at the age of 15, and is still living more than 6 years. Patient 2, a 33-year-old female with acute lymphoblastic leukemia, has complete remission of five years' duration. Patient 3, a 21-year-old female with acute myelocytic leukemia, is still alive without evidence of relapse for 6 years. In these three patients, complete remission was achieved within two months by initial combination chemotherapies, and there was no relapse thereafter.<br>It is noteworthy that three patients had recovered from severe infection, such as pulmonary tuberculosis (patient 1) and septicemia (patients 2 and 3) during the course of the disease. Recently, immunotherapy for patients with acute leukemia has been tried to improve remission duration and survival. In this context, it is suggested that stimulation or restoration of immunocompetence after severe infection may be one of contributing factors for prolonged remission in three patients reported herein.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 21 (2), 266-272, 1980

    The Japanese Society of Hematology

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