Clinical assessment of CD4/8 ratio of bone marrow lymphocytes in acquired pure red cell aplasia

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  • 後天性赤芽球勞における骨髄中リンパ球のCD4/8比の臨床的検討
  • コウテンセイ セキ ガキュウロウ ニ オケル コツズイ チュウ リンパキュウ ノ CD4/8ヒ ノ リンショウテキ ケントウ

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We have reviewed 6 patients with acquired PRCA and investigated CD4/8 ratio in the bone marrow lymphocytes prior to treatment with cyclosporin A (CsA). CsA, as a remission induction therapy, produced CR in 3/6 patients, and PR+NR in 3/6 patients. CD4/8 ratio in CR group was high compared to PR+NR group. Moreover, the number of reticulocyte and hemoglobin concentration in CR group was high in comparison with PR+NR group. In acquired PRCA, CD4/8 ratio in the bone marrow lymphocytes may correlate with the disease status and the outcome of CsA treatment.

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  • Rinsho Ketsueki

    Rinsho Ketsueki 55 (6), 703-705, 2014

    The Japanese Society of Hematology

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