Diffuse large B-cell lymphoma of the testis relapsed 16 years after achieving complete response
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- NAGASAKA Isao
- Department of Medicine and Clinical Science, Gunma University
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- MITSUI Takeki
- Department of Medicine and Clinical Science, Gunma University
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- ISHIZAKI Takuma
- Department of Medicine and Clinical Science, Gunma University
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- KOISO Hiromi
- Department of Oncology Center, Gunma University Hospital
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- YOKOHAMA Akihiko
- Blood Transfusion Service, Gunma University Hospital
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- SAITOH Takayuki
- Gunma University Graduate School of Health Sciences
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- HIRATO Junko
- Department of Pathology, Gunma University Hospital
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- IGARASHI Tadahiko
- Gunma Prefectural Cancer Center
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- KOJIMA Masaru
- Anatomic and Diagnostic Pathology, Dokkyo University School of Medicine
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- TSUKAMOTO Norifumi
- Department of Oncology Center, Gunma University Hospital
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- NOJIMA Yoshihisa
- Department of Medicine and Clinical Science, Gunma University
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- MURAKAMI Hirokazu
- Gunma University Graduate School of Health Sciences
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- HANDA Hiroshi
- Department of Medicine and Clinical Science, Gunma University
Bibliographic Information
- Other Title
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- 寛解16年後に再発した精巣原発びまん性大細胞型B細胞リンパ腫
- 症例報告 寛解16年後に再発した精巣原発びまん性大細胞型B細胞リンパ腫
- ショウレイ ホウコク カンカイ16ネンゴ ニ サイハツ シタ セイソウ ゲンパツビマンセイ ダイ サイボウガタ B サイボウ リンパシュ
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Abstract
Testicular lymphoma is a rare disease, accounting for 1-2% of non-Hodgkin lymphoma and 5-9% of all testicular tumors, and has a high relapse rate with a poor prognosis. We report a patient with testicular diffuse large B-cell lymphoma (DLBCL) who relapsed after being in remission for 16 years. He had undergone orchiectomy of the right testis and was diagnosed as having DLBCL (stage IAE) at 49 years of age. After 3 cycles of CHOP, he achieved a complete remission. Orchiectomy was performed because of a left testicular tumor, and he was again diagnosed with DLBCL at the age of 65. VH3-21 was detected in lymphoma cells at the times of both the first diagnosis and the relapse based on analysis of the variable region of the immunoglobulin heavy chain. Accordingly, the lymphoma cells at relapse were confirmed to be the same clone as that which had been documented at the first diagnosis.
Journal
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- Rinsho Ketsueki
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Rinsho Ketsueki 56 (12), 2447-2451, 2015
The Japanese Society of Hematology
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Details 詳細情報について
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- CRID
- 1390282680014013696
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- NII Article ID
- 130005116922
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- NII Book ID
- AN00252940
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- ISSN
- 18820824
- 04851439
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- NDL BIB ID
- 027034287
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- PubMed
- 26725353
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed