Successful treatment with biweekly CHOP for bone marrow relapse of blastic plasmacytoid dendritic cell neoplasm
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- ONO Keiko
- Department of Hematology-Oncology, Chiba Cancer Center
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- ISE Mikiko
- Department of Hematology-Oncology, Chiba Cancer Center
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- IKEBE Dai
- Department of Clinical Pathology, Chiba Cancer Center
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- SATO Akiyasu
- Department of Hematology-Oncology, Chiba Cancer Center
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- WANG Xiaofei
- Department of Hematology-Oncology, Chiba Cancer Center
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- SUGAWARA Takeaki
- Department of Hematology-Oncology, Chiba Cancer Center
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- TSUJIMURA Hideki
- Department of Hematology-Oncology, Chiba Cancer Center
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- ITAMI Makiko
- Department of Clinical Pathology, Chiba Cancer Center
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- KUMAGAI Kyoya
- Department of Hematology-Oncology, Chiba Cancer Center
Bibliographic Information
- Other Title
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- Biweekly CHOP療法が奏効した骨髄浸潤を伴う再発芽球性形質細胞様樹状細胞腫瘍
- 症例報告 第4回日本血液学会関東甲信越地方会 優秀演題 Biweekly CHOP療法が奏効した骨髄浸潤を伴う再発芽球性形質細胞様樹状細胞腫瘍
- ショウレイ ホウコク ダイ4カイ ニホン ケツエキ ガッカイ カントウ コウシンエツチホウカイ ユウシュウ エンダイ Biweekly CHOP リョウホウ ガ ソウコウ シタ コツズイ シンジュン オ トモナウ サイハツガキュウセイ ケイシツ サイボウ ヨウジュジョウ サイボウ シュヨウ
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Abstract
<p>Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematological malignancy derived from precursors of plasmacytoid dendritic cells. The majority of patients initially respond to multi-agent chemotherapy, though most relapse within a year and the prognosis is very poor. We report a 67-year-old man with erythema on the right chest and a nasopharyngeal mass. Histological examination revealed a mass of tumor cells expressing CD4, CD56, and CD123, but neither CD3 nor CD20. He was diagnosed with BPDCN. Bone marrow involvement was not seen at diagnosis. He achieved complete remission (CR) with CHOP-like chemotherapy. After 1 year, he relapsed with a cutaneous tumor on the head, a nasopharyngeal tumor, and massive bone marrow involvement. Relapsed BPDCN is generally resistant to chemotherapy and the prognosis is dismal. However, he was successfully treated with biweekly CHOP therapy and achieved a second CR lasting 16 months.</p>
Journal
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- Rinsho Ketsueki
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Rinsho Ketsueki 58 (2), 150-154, 2017
The Japanese Society of Hematology
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Details 詳細情報について
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- CRID
- 1390282680014204800
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- NII Article ID
- 130005450483
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- NII Book ID
- AN00252940
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- ISSN
- 18820824
- 04851439
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- NDL BIB ID
- 028017948
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- PubMed
- 28321093
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- Text Lang
- ja
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- Data Source
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- JaLC
- NDL
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed