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Exercise and Rest Technetium-99m-Tetrofosmin Lung Uptake
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- Tsou Shi-Sheng
- the Division of Cardiology (S.S.T.), Departments of Nuclear Medicine (S.S.S., A.K.), Family Medicine (C.C.Lin) and Medical Research (A.K., C.C.Lee), China Medical College Hospital
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- Sun Shung-Shung
- the Division of Cardiology (S.S.T.), Departments of Nuclear Medicine (S.S.S., A.K.), Family Medicine (C.C.Lin) and Medical Research (A.K., C.C.Lee), China Medical College Hospital
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- Kao Albert
- the Division of Cardiology (S.S.T.), Departments of Nuclear Medicine (S.S.S., A.K.), Family Medicine (C.C.Lin) and Medical Research (A.K., C.C.Lee), China Medical College Hospital
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- Lin Cheng-Chieh
- the Division of Cardiology (S.S.T.), Departments of Nuclear Medicine (S.S.S., A.K.), Family Medicine (C.C.Lin) and Medical Research (A.K., C.C.Lee), China Medical College Hospital
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- Lee Cheng-Chun
- the Division of Cardiology (S.S.T.), Departments of Nuclear Medicine (S.S.S., A.K.), Family Medicine (C.C.Lin) and Medical Research (A.K., C.C.Lee), China Medical College Hospital
Bibliographic Information
- Other Title
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- <b>Correlation with Left Ventricular Ejection Fraction in Patients with Coronary Artery Disease</b>
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Description
Increased lung uptake of thallium-201 (Tl-201) and technetium-99m (Tc-99m) MIBI in myocardial perfusion imaging is a reliable marker of left ventricular dysfunction. The goal of our study was to establish whether the lung-to-heart (L/H) uptake ratio with a newer cardiac imaging agent, Tc-99m tetrofosmin, can also provide valuable information about left ventricular function.<br> We studied 60 patients with recent coronary artery diseases (CAD) undergoing first-pass radionuclide ventriculography to calculate left ventricular ejection fraction (LVEF) and myocardial perfusion imaging to calculate the L/H ratio. Group A consisting of 30 CAD patients with higher LVEF (≥40%) had a significanly lower L/H ratio than group B consisting of 30 CAD patients with abnormal LVEF (<40%) during exercise and rest. In groups A and B, the exercise and rest L/H ratios did not differ significantly. However, a statistically significant inverse correlation was found between the L/H ratio and LVEF during exercise and rest among the 60 patients.<br> L/H ratios, measured by 99mTc-tetrofosmin imaging, provide clinically useful information with which to predict left ventricular dysfunction in CAD patients.<br>
Journal
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- Japanese Heart Journal
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Japanese Heart Journal 43 (5), 515-523, 2002
International Heart Journal Association
