A case of chronic sarcoid myopathy with Basedow’s disease and Sjogren’s syndrome: A case series of sarcoid myopathy
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- Isobe Takashi
- Department of Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan Department of Neurology, Aizawa Hospital, Nagano, Japan
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- Mori-Yoshimura Madoka
- Department of Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan
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- Oya Yasushi
- Department of Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan
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- Saito Yuko
- Department of Laboratory Medicine, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan
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- Murata Miho
- Department of Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan
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- Nishino Ichizo
- Department of Neuromuscular Research, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan Department of Medical Genome Center, National Center of Neurology and Psychiatry, Tokyo, Japan
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- Takahashi Yuji
- Department of Neurology, National Center Hospital, National Center of Neurology and Psychiatry, Tokyo, Japan
Bibliographic Information
- Other Title
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- 自己免疫性甲状腺疾患とシェーグレン症候群を合併している慢性ミオパチー型筋サルコイドーシスの1例：症例報告及び筋サルコイドーシス自験例の検討
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Abstract
<p>We report a 62-year-old woman with a history of Basedow’s disease and Sjogren’s syndrome who presented with slowly progressive limb muscle weakness over the course of ten years. On physical examination, she had dry eye and mouth, but was otherwise normal. Neurological examination revealed symmetrical proximal dominant muscle weakness. Polymyositis was suspected at initial diagnosis due to her clinical course, physical examination, and autoimmune disease. However, the final diagnosis based on a muscle biopsy was the chronic myopathic type of sarcoid myopathy. Among 25 definite sarcoid myopathy cases in the National Center of Neurology and Psychiatry muscle repository from 2010 to 2015, 6/25 had autoimmune diseases. All 6 patients were female and had the chronic myopathic type of sarcoid myopathy. The number of patients with Sjogren’s syndrome, thyroid disease, autoimmune hepatitis, and idiopathic thrombocytopenia were 4, 1, 1, and 1, respectively. Only the present case had both thyroid disease and Sjogren’s syndrome. In conclusion, the chronic myopathic type of sarcoid myopathy is one possibility to consider in patients who present with progressive myopathy together with autoimmune diseases.</p>
Journal
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- Rinsho Shinkeigaku
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Rinsho Shinkeigaku 57 (5), 220-224, 2017
Societas Neurologica Japonica