Real time analog computation of left ventricular systolic pressure volume area as predictor of oxygen consumption.

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  • SUGA Hiroyuki
    Department of Cardiac Physiology, National Cardiovascular Center Research Institute
  • MATSUSHITA Gota
    Department of Cardiac Physiology, National Cardiovascular Center Research Institute

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Other Title
  • Real Time Analog Computation of Left Ve

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Abstract

An analog circuit was devised for real time determination of the left ventricular systolic pressure volume area (PVA), which we had recently identified as a reliable predictor of cardiac oxygen consumption rate per beat. PVA is the specific area in the pressure-volume diagram that is bounded by the end-systolic and end-diastolic pressure-volume relationship lines and the systolic segment of the pressure-volume loop trajectory of the left ventricle. The computed PVA was compared with PVA obtained as usual by planimetry. Correlation coefficient between the two PVA's was 0.997 (N=31, p<0.001) and the standard error of mean of the difference between the two PVA's was as small as practically negligi-ble 8mmHg ml in the PVA range from 0 to 2, 000mmHg ml. We concluded that this PVA analog computer can be used for real time determination of PVA, expediting the future studies of the relationship between PVA and cardiac oxygen consumption

Journal

  • Japanese Heart Journal

    Japanese Heart Journal 22 (6), 997-1003, 1981

    International Heart Journal Association

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