Morphological Comparison of Infundibular Pulmonary Stenosis and Tetralogy of Fallot

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  • SAKASHITA Isao
    Department of Thoracic and Cardiovascular Surgery, Niigata University School of Medicine
  • MATSUKAWA Tetsunosuke
    Department of Thoracic and Cardiovascular Surgery, Niigata University School of Medicine
  • ANDO Takeshi
    Department of Thoracic and Cardiovascular Surgery, Niigata University School of Medicine
  • ASANO Ken-ichi
    Department of Thoracic and Cardiovascular Surgery, Niigata University School of Medicine

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Micro- and electron microscopic findings obtained from the specimens of VSD, infundibular pulmonary stenosis, and tetralogy of Fallot with and without an advanced stage revealed a serial alterations from control architecture to so-called dystrophy of the cardiac muscle cell. Marked changes of these diseases were noted in thickness and cross sectional areas in respective longitudinal and cross section profiles, and also between contractile-myofibrils and non-contractile -mitochondria, glycogen particles- components.<br>However, because of congenital pathologic conditions of the specimens, demonstrations in this series would be limited to explain exact transformation from control to dystrophy.

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