Pulmonary Regional Ventilation-Perfusion Relationships in Chronic Cardiopulmonary Disorders

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  • UEDA Hideo
    the Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
  • HATANO Shuichi
    the Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
  • IIO Masahiro
    the Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
  • KAIHARA Shigekoto
    the Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
  • MORINARI Hajime
    the Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
  • KOIKE Shigeo
    the Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo
  • MURAO Makoto
    the Second Department of Internal Medicine, Faculty of Medicine, University of Tokyo

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  • Pulmonary regional ventilation-perfusion relationships in chronic cardiopulmonary disorders-1-Radioactive rare gas method(Xe-133,Xe-135 and Kr-85 method)
  • I. Radioactive Rare Gas Method (Xe-133, Xe-135 and Kr-85 Method)

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IN the past decade since Knipping introduced radioactive rare gas for the study of regional pulmonary function, advantages of the radioisotope method over conventional methods were soon recognized and various methods were developed. These new methods enabled more precise study of overall gas exchange in the whole lung. <BR>Relationship between the regional distribution of blood flow and that of ventilation is of great importance because inequality of these two functions is now considered to be one of the main causes of hypoxemia in medical cases. <BR>Therefore, 52 cases with chronic cardiopulmonary disorders were studied to find the final functional state of regional ventilation-perfusion relationship in pulmonary lesions which began from either predominant ventilation or perfusion disturbance. To this end, the radioactive rare gas method reported by Dollery et al. and the scanning method by Drs. Taplin and Wagner were performed. At present authors are using both of these methods. The results obtained by the rare gas method were reported in this article.

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