THE ACTIONS OF TETRODOTOXIN, PROCAINE, AND ACETYLCHOLINE ON GUSTATORY RECEPTIONS IN FROG AND RAT

DOI Web Site PubMed
  • 尾関 正寛
    Department of Physiology, Kumamoto University Medical School
  • 野間 昭典
    Department of Physiology, Kumamoto University Medical School

この論文をさがす

説明

1) The effects of tetrodotoxin (TTX), procaine and acetylcholine choline (ACh) were investigated both the recording the receptor potential in gustatory cells by measuring and the integrated response of their afferent nerves in rats and frogs.<BR>3) TTX (10-6 g/ml) did not induce electrical responses in the gustatory cells of frog and rat or in chorda tympani nerve of rat and glossopharyngeal nerve of frog, nor did it suppress the generation of the receptor potential in response to gustatory stimuli. Procaine (0.1 or 0.5 %) also had no effect on the receptive process in the rat. However, in the frog the magnitude of the integrated response of the nerve in response to NaCl and CaCl2 was depressed after the tongue had been soaked in TTX.<BR>3) ACh (10-4 g/ml) did not elicit electrical response in the gustatory cell and the nerve of the rat. In the frog, 10-3 g/ml ACh did not produce any immediate response in gustatory cell but the magnitude of integrated response of the nerve to NaCl was modified after the tongue had been soaked in ACh for some time.<BR>4) It was suggested that the penetration of solutions from the tongue surface might hardly occur into the space surrounding the gustatory cell bodies of the rat, while in the frog occur in some extent.

収録刊行物

詳細情報 詳細情報について

問題の指摘

ページトップへ