Thermoregulatory Nonshivering Thermogenesis in Men, with Special Reference to Lipid Metabolism
書誌事項
- タイトル別名
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- Thermoregulatory Nonshivering Thermogen
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The existence of thermoregulatory nonshivering thermogenesis, with special reference to lipid metabolism, was investigated in men. Acute cold exposure (10°C, 60 min) produced a marked increase in heat production, with concomitant elevation of plasma free fatty acid (FFA) level, modest increase of ketone body concentration and lowered respiratory quotient (R.Q.). The correlation of heat production to plasma FFA levels was significantly positive; that is, subjects with higher heat production showed higher plasma FFA levels. Moreover, correlation of either heat production or plasma FFA levels to R.Q. was significantly negative, respectively. On the other hand, exposure to cold after an administration of nicotinic acid, which has a suppressive effect on FFA mobilization from adipose tissue, resulted in less cold-elevated heat production, a significant fall of plasma FFA and ketone body concentrations, and no change in R.Q. Although no visible or only slight shivering was observed in control cold exposure study, greater shivering occurred in the nicotinic acid cold exposure study.<BR>These results appear to indicate that nonshivering thermogenesis as a source of heat production achieved by enhanced utilization of lipids is also present in men.
収録刊行物
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- The Japanese Journal of Physiology
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The Japanese Journal of Physiology 29 (4), 359-372, 1979
一般社団法人 日本生理学会
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詳細情報 詳細情報について
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- CRID
- 1390282680020172800
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- NII論文ID
- 130003476733
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- NII書誌ID
- AA00691224
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- COI
- 1:CAS:528:DyaE1MXmtVynsr0%3D
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- ISSN
- 18811396
- 0021521X
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- NDL書誌ID
- 2077530
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- PubMed
- 533941
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可