Prophylactic Effect of Black Tea Extract as Gargle against Influenza

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  • IWATA Masashi
    Department of Microbiology and Immunology, Showa University School of Medicine
  • TODA Masako
    Department of Microbiology and Immunology, Showa University School of Medicine
  • NAKAYAMA Mikio
    Department of Virology, National Institute of Health
  • TSUJIYAMA Hiroyuki
    Department of Microbiology and Immunology, Showa University School of Medicine
  • ENDO Wataru
    Department of Microbiology and Immunology, Showa University School of Medicine
  • TAKAHASHI Osahiko
    Department of Microbiology and Immunology, Showa University School of Medicine
  • HARA Yukihiko
    Food Research Laboratories, Mitsui Norin Co.
  • SHIMAMURA Tadakatsu
    Department of Microbiology and Immunology, Showa University School of Medicine

Bibliographic Information

Other Title
  • 紅茶エキスのうがいによるインフルエンザ予防効果
  • コウチャ エキスノウガイ ニヨル インフルエンザ ヨボウ コウカ

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Abstract

We examined whether gargling with black tea prevents influenza infection. Tests were carried out during a five month period (October 1992 to March 1993). The control group that followed their normal daily routine, whereas the test group that gargled with 0.5 w/v% black tea extract twice daily (at 8 a.m. and 5 p.m.).<BR>Influenza viruses were isolated from influenza patients and an antigen analysis was carried out. As a result, two strains of influenza A viruses (H3N2) and ten strains of B virus were detected.<BR>An HI test was done using paired sera of the control group and the test group. The HI titers raised a four fold or greater in 48.8%(61/125) in the control group and 35.1%(35/134) in the test group. There was a significant difference (p <0.05) between the control and test groups.<BR>These results indicate that black tea extract is effective as a prophylactic agent against influenza infection.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 71 (6), 487-494, 1997

    The Japanese Association for Infectious Diseases

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