A Factor to Enhance HIV Replication in Serum Bearing a Resemblance to Membranes of <I>Acholeplasma laidlawii</I>

DOI Web Site PubMed 20 References
  • HAYASHI Ryunosuke
    Department of Bacteriology, Kurume University School of Medicine Department of Obstetrics & Gynecology, Kurume University School of Medicine

Bibliographic Information

Other Title
  • 血清中に存在する<I>Acholeplasma laidlawii</I>膜成分類似のhuman immunodeficiency virus (HIV) 増殖促進物質
  • 血清中に存在するAcholeplasma laidlawii膜成分類似のhuman immunodeficiency virus(HIV)増殖促進物質
  • ケッセイチュウ ニ ソンザイスル Acholeplasma laidlawii
  • A Factor to Enhance HIV Replication in Serum Bearing a Resemblance to Membranes of Acholeplasma laidlawii

Search this article

Abstract

We found a substance A in human serum by ELISA method, using anti-A antibody. The substance A was obtained from the membranes of A. laidlawii and this enhanced HIV replication. This substance in human serum was detected in the chloroform phase of the Bligh-Dyer method. Rf value in thin layer chromatography was 0.28. This substance clearly showed enhancement of HIV replication as well as the activity of the membranes of A. laidlawii, but did not induce TNF production. Furthermore, the activity which enhances HIV replication in human serum was reduced by anti-A antibody. These results suggest that the substance derives from human serum which possesses a similar active site as those of substance derived from the membrane of A. laidlawii.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 69 (12), 1389-1395, 1995

    The Japanese Association for Infectious Diseases

References(20)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top