Effects of Transport Stress on Serum Alkaline Phosphatase Activity in Beagle Dogs

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  • Ochi Takehiro
    Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Nishiura Ippei
    Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Tatsumi Mitsuyoshi
    Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Hirano Yoshimi
    Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Yahagi Kouichi
    Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Sakurai Yasuhiro
    Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Sudo Yuji
    Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Koyama Hironari
    Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Hagita Yuichi
    Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Fujimoto Yoshikatsu
    Laboratory Animal Science Div., Astellas Research Technologies Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan KAC Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Kitamura Shinji
    KAC Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Hashimoto Hideki
    KAC Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Nakamura Tomoya
    KAC Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Yamada Asobi
    KAC Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Tanimoto Masayoshi
    KAC Co., Ltd., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan
  • Nishina Noriko
    Drug Safety Research Labs, Astellas Pharma Inc., 1-6 Kashima 2-chome, Yodogawa-ku, Osaka 532-8514, Japan

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Abstract

Here, to determine the effects of transport stress on blood parameters in dogs, we investigated the changes in hematologic and serum chemical parameters in healthy beagle dogs transported from Beijing, China, to Osaka, Japan, to obtain the background data. Only the activity of serum alkaline phosphatase increased clearly upon arrival, a change attributed to transport stress, but the activity gradually reduced afterward. No marked changes in levels of other blood parameters were noted. Our findings here suggest that alkaline phosphatase is a useful tool for studying transport stress.

Journal

  • Experimental Animals

    Experimental Animals 62 (4), 329-332, 2013

    Japanese Association for Laboratory Animal Science

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