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Longitudinal Study of Serological Response to <I>Bartonella henselae</I> by Indirect Fluorescence Assay in Cat Scratch Disease
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- KUSABA Nobuhide
- Department of Medicine, Yame General Hospital
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- YOSHIDA Hiroshi
- Department of Medicine, Yame General Hospital
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- SUMINO Michihiro
- Department of Medicine, Yame General Hospital
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- SATA Michio
- Second Department of Medicine, Kurume University School of Medicine
Bibliographic Information
- Other Title
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- 猫ひっかき病における<I>Bartonella henselae</I>抗体の経時的測定の臨床的意義
- 猫ひっかき病におけるBartonella henselae抗体の経時的測定の臨床的意義--間接蛍光抗体法による検討
- ネコヒッカキビョウ ニ オケル Bartonella henselae コウタイ ノ ケイジテキ ソクテイ ノ リンショウテキ イギ カンセツ ケイコウ コウタイホウ ニ ヨル ケントウ
- Longitudinal Study of Serological Response to Bartonella henselae by Indirect Fluorescence Assay in Cat Scratch Disease
- 間接蛍光抗体法による検討
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Description
Sequential serologic testing for IgG and IgM titers to Bartonella henselae were evaluated by an indirect fluorescence assay (IFA) in patients with CSD. The IFA test for the detection of IgG and IgM antibodies to B. henselae in 52 CSD patients showed that 40 (76.9%) were positive for IgG antibody and 9 (17.3%) were positive for IgM antibody. Two or more consecutive serum samples from 30 patients with CSD were assessed. In regard to the detection of IgG antibody, 5 patients had rapidly elevated titers in the acute phase, 12 patients had high titers from the acute phase, and 5 patients had a positive titer 24 weeks after the onset. B. henselae IgM antibody kinetics varied widely between patients with CSD. The seropositive rate for the antibody to B. henselae was analyzed at overtime after the onset and we found that the IgG-seropositive rate was high from 2 weeks after the onset and low after 25 weeks. The sensitivity of the IgM IFA was low, and IgM antibody to B. henslelae was not detected from 9 weeks. The detection from consecutive serum samples of antibodies to B. henselae by IFA is very useful for diagnosis in the case of clinically susupected CSD.
Journal
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- Kansenshogaku Zasshi
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Kansenshogaku Zasshi 75 (7), 557-561, 2001
The Japanese Association for Infectious Diseases
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Details 詳細情報について
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- CRID
- 1390282680024837120
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- NII Article ID
- 130004112746
- 10008703522
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- NII Book ID
- AN00047715
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- ISSN
- 1884569X
- 03875911
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- NDL BIB ID
- 5850685
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- PubMed
- 11521278
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- Article Type
- journal article
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- Data Source
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- JaLC
- NDL Search
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed