Antimicrobial Susceptibility Testing of Clinical Isolates of <I>Haemophilus influenzae</I> Derived from Japanese Children

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  • 小児臨床検体由来<I>Haemophilus influenzae</I>の抗菌薬感受性に関する検討
  • 小児臨床検体由来Haemophilus influenzaeの抗菌薬感受性に関する検討
  • ショウニ リンショウ ケンタイ ユライ Haemophilus influenzae ノ コウキンヤク カンジュセイ ニ カンスル ケントウ
  • Antimicrobial Susceptibility Testing of Clinical Isolates of Haemophilus influenzae Derived from Japanese Children

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Abstract

We examined the antimicrobial susceptibility testing of 1, 024 Haemophilus influenzae isolates recovered from Japanese children. Percent distribution of β-lactamase-negative ampicillin (ABPC)-resistant strain (BLNAR; ABPC-MIC≥4μg/ml) was 15.0%. Prevalence of BLNAR increased remarkably from 12.7 to 22.1% in recent 4 years. Furthermore, the frequency of highly resistant strains (ABPC-MIC≥8μg/ml) increased from 28.6 to 56.9% among BLNAR. Decreased susceptibility for cephems was observed in non-BLNAR strains including serotype b strain isolated from the cerebrospinal fluid

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 78 (11), 943-951, 2004

    The Japanese Association for Infectious Diseases

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