A Trial of Amantadine for the Treatment of Influenza A Infection in Children
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- TAKEDA Nobue
- Division of Infectious Diseases, Chiba Children's Hospital
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- KUROSAKI Tomomichi
- Department of Pediatrics, Chiba University School of Medicine
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- NAKAMURA Akira
- Department of Pediatrics, Chiba Municipal Kaihin Hospital
Bibliographic Information
- Other Title
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- A型インフルエンザ流行期の小児における塩酸アマンタジンの使用経験
- Aガタ インフルエンザ リュウコウキ ノ ショウニ ニ オケル エンサン アマンタジン ノ シヨウ ケイケン
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Abstract
We administered amantadine to 52 children for therapy and 3 children for prophylaxis of influenza A infection from January to March 1998. Among the 23 children in the therapy group withproven influenza A/H3N2 infection, 15 patients (60%) allayed fever within 3 days but 9 (40%) hadpersistent fever for more than 4 days after administration of amantadine. Seven of these nine patients (40%) received amantadine within 2 days after the onset of fever. Two of these nine had secondarybacterial infections. One child had insomnia as side effect. We concluded that administrationof amantadine for therapy is safe and effective, if given to patients without secondary bacterial infections in the first 48 hours of the illness.
Journal
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- Kansenshogaku Zasshi
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Kansenshogaku Zasshi 74 (1), 6-11, 2000
The Japanese Association for Infectious Diseases
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Keywords
Details 詳細情報について
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- CRID
- 1390282680026923904
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- NII Article ID
- 130004112713
- 10008713432
- 10008704366
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- NII Book ID
- AN00047715
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- ISSN
- 1884569X
- 03875911
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- NDL BIB ID
- 4974513
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- PubMed
- 10695288
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed