Immunological Studies on Whole Saliva

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  • GOTO Toshihiro
    The 3rd Department of Internal Medicine, Tokushima University, School of Medicine
  • TAKISHITA Yoshihiro
    The 3rd Department of Internal Medicine, Tokushima University, School of Medicine
  • KOZAI Katsuhito
    The 3rd Department of Internal Medicine, Tokushima University, School of Medicine
  • TSUKUDA Tomio
    The Department of Oral Surgery, Tokushima University, School of Medicine
  • KAWANO Michiaki
    The 3rd Department of Internal Medicine, Tokushima University, School of Medicine
  • TSUBURA Eiro
    The 3rd Department of Internal Medicine, Tokushima University, School of Medicine

Bibliographic Information

Other Title
  • 唾液の免疫学的検討
  • 唾液の免疫学的検討--免疫グロブリンAを中心として
  • ダエキ ノ メンエキガクテキ ケントウ メンエキ グロブリン A オ チュウシ
  • With Special Reference to Immunoglobulin A
  • 免疫グロブリンAを中心として

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Abstract

The occurrence of serum and salivary immunoglobulins (IgA, IgM, IgG) was investigated in normal adults and the patients with pyorrhea alveolaris and collagen disease. The influences of sex on total protein and immunoglobulins were checked as for normal adults.<BR>The changes of total protein and immunoglobulins with disorders such as pyorrhea alveolaris and collagen disease were investigated and discussed.<BR>The results were follows:<BR>1) No correlation between serum and salivary immunoglobulins was found.<BR>2) In normal adults, female serum IgM levels were significantly higher than male.<BR>3) In the patients with pyorrhea alveolaris, both serum and salivary IgG levels increased. It was thought that the increase of salivary IgG levels was due to the excretion from serum.<BR>4) In the patients with collagen disease, the levels of serum IgA, IgM and IgG significantly increased, whereas the levels of total protein and IgA in saliva decreased.<BR>These facts suggest that the disorders of general humoral immunity affect the local IgA system. We thought it noticeable evidence in the point of protection mechanism from infectious agents.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 51 (10), 550-557, 1977

    The Japanese Association for Infectious Diseases

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