A Case of Disseminated <i>Mycobacterium genavense </i>Infectioni n an AIDS Patient. A Case Report and a Review of the Literature

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  • 播種性<i>Mycobacterium genavense </i>感染症を呈したAIDS の1 例
  • 症例 播種性Mycobacterium genavense感染症を呈したAIDSの1例
  • ショウレイ ハシュセイ Mycobacterium genavense カンセンショウ オ テイシタ AIDS ノ 1レイ

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A 44-year-old male, who was HIV seropositive, developped weight loss, high grade fever, and multiple lymphadenopathies. Bone marrow biopsy revealed a granuloma lesion, and at the same part of the specimen, Ziehl Neelsen staining showed multiple mycobacterium diffusely arranged in the histocytes. The culture did not show positive after 6 to 8 weeks. Finally we diagnosed disseminated Mycobacterium genavense using a house-keeping gene analysis including 16S rRNA sequencing of lymph punctate with fine needle aspiration and the specimen from the biopsy of the lymph node. If a specimen tests positive for Ziehl Neelsen staining smear positive, culture negative, and PCR negative for tuberculosis and Mycobacterium avium complex, we should consider M. genavense infection as one of the differential diagnoses.

Journal

  • Kansenshogaku Zasshi

    Kansenshogaku Zasshi 89 (2), 259-254, 2015

    The Japanese Association for Infectious Diseases

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