Long-Term Survival After Surgical Resection of Primary Spinal Malignant Melanoma -Case Report-

  • NISHIHARA Masamitsu
    Department of Neurosurgery, Kobe University Graduate School of Medicine
  • SASAYAMA Takashi
    Department of Neurosurgery, Kobe University Graduate School of Medicine
  • KONDOH Takeshi
    Department of Neurosurgery, Kobe University Graduate School of Medicine
  • TANAKA Kazuhiro
    Department of Neurosurgery, Kobe University Graduate School of Medicine
  • KOHMURA Eiji
    Department of Neurosurgery, Kobe University Graduate School of Medicine
  • KUDO Hiroshi
    Department of Neurosurgery, Hyogo Cancer Center

Bibliographic Information

Other Title
  • —Case Report—

Search this article

Description

A 49-year-old man was admitted suffering from headache persisting for a month. He had a history of primary spinal intramedullary malignant melanoma at the T6 level 18 years previously, which had remained stable for 18 years. Magnetic resonance imaging revealed central nervous system (CNS) dissemination of malignant melanoma. Whole brain radiation therapy (30 Gy), local radiation therapy (15 Gy), and routine intrathecal injection of interferon beta were performed. The progression of CNS dissemination of malignant melanoma was controlled without neurological deterioration for 38 months. The prognosis for primary CNS malignant melanomas better than that for cutaneous melanoma. However, the clinical course is still unknown, and CNS dissemination is regarded fatal. The unusually long survival in the present case indicates the effectiveness of the combined radiotherapy and interferon therapy.<br>

Journal

Citations (1)*help

See more

References(45)*help

See more

Details 詳細情報について

Report a problem

Back to top