Ruptured Intracranial Aneurysms in Pediatric Polyarteritis Nodosa

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  • TOYODA Keisuke
    Department of Neurosurgery, Nagasaki University Hospital Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center
  • TSUTSUMI Keisuke
    Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center
  • HIRAO Tomohito
    Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center
  • ONO Tomonori
    Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center
  • TAKAHATA Hideaki
    Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center
  • TODA Keisuke
    Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center
  • BABA Hiroshi
    Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center
  • ITO Masahiro
    Department of Pathology, National Hospital Organization Nagasaki Medical Center
  • YONEKURA Masahiro
    Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center

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  • —Case Report—

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Polyarteritis nodosa (PAN) is a rare, systemic necrotizing vasculitis of small and medium size arteries that leads to aneurysms in various organs. Aneurysms associated with PAN are common in visceral arteries, however, intracranial aneurysms are rare, especially in childhood. A pediatric patient with PAN developed serial hemorrhagic strokes from a ruptured superior cerebellar artery aneurysm (subarachnoid hemorrhage) and a de novo aneurysm of the frontoorbital artery (intracerebral hemorrhage) after 9 months. Patients with PAN who present with intracranial aneurysms are candidates for intervention even if the aneurysm is unruptured and still small, and close observation is needed to detect de novo aneurysms in patients with chronic history of PAN.<br>

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