COMPARISON OF VALUE OF FREE-TO TOTAL PROSTATE SPECIFIC ANTIGEN, PROSTATE SPECIFIC ANTIGEN DENSITY AND PROSTATE SPECIFIC ANTIGEN DENSITY OF TRANSITION ZONE FOR DIAGNOSIS OF PROSTATE CANCER IN PATIENTS WITH A PSA LEVEL OF 4.1-10ng/ml

Fujinami Kiyoshi, Miura Takeshi, Takizawa Akitoshi, Osada Yutaka, Kawakami Satoshi

doi:10.5980/jpnjurol1989.96.475

Bibliographic Information

Other Title

PSA 4.1～10ng/mlの症例における, 前立腺癌の診断におけるF/T PSA, PSAD, PSATZの有用性の比較
PSA 4 1 10ng ml ノショウレイニオケルゼンリツセンガンノシンダンニオケル F T PSA PSAD PSATZ ノユウヨウセイノヒカク

Search this article

Description

(Purpose) We evaluated the utility of free-to total PSA (F/T PSA) ratio, PSA density (PSAD) and PSA density of the transition zone (PSATZ) in diagnosis of prostate cancer with intermediate PSA level (4.1-10ng/ml).<br>(Patients and Methods) Between January 2000 and December 2003, systematic prostate biopsies were performed on 178 patients with intermediate PSA level. The clinical values of F/T PSA ratio, PSAD and PSATZ for the detection of prostate cancer were compared by using receiver operating characteristic (ROC) curves.<br>(Results) Overall, 57 of the 178 (32%) patients had prostate carcinoma. The ROC curve analysis showed PSAD and PSATZ were superior to F/T PSA ratio in patients with intermediate PSA level. In patients with total prostate volume greater than 30cm³, the area under the ROC curve for F/T PSA ratio was greater than that for PSAD and PSATZ.<br>(Conclusions) PSAD and PSATZ were more powerful predictors of prostate cancer than F/T PSA ratio in patients with intermediate PSA level. While F/T PSA ratio was effective for diagnosis of prostate cancer in prostate volume greater than 30cm³.

Journal

The Japanese Journal of Urology

The Japanese Journal of Urology 96 (4), 475-479, 2005

THE JAPANESE UROLOGICAL ASSOCIATION

Keywords

Details 詳細情報について

Export

Report a problem