書誌事項
- タイトル別名
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- Development of Analytical Method for Levofloxacin and Clarithromycin in Secondary Effluent and Their Adverse Effects on Algal Growth
- ゲスイ ショリ スイチュウ ニ フクマレル レボフロキサシン クラリスロマイシン ノ ブンセキ ト ソウルイ セイチョウ エ ノ エイキョウ
この論文をさがす
抄録
In recent years, antibiotics resident in sewage and in the water environment have become an emerging public concern in many developed countries. However, limited knowledge is available on the occurrence of antibiotics in sewage and discharge from wastewater treatment plants (WWTPs) in Japan. Moreover, little is known on the significance of their occurrence in the water environment from the viewpoints of biological adverse effects. The objectives of this research were, therefore, to determine the occurrence of selected antibiotics, namely levofloxacin (LVFX) and clarithromycin (CAM). That are commonly used in Japan, in discharge from WWTPs and then to evaluate their possible effects on algal growth. Therefore, we developed a novel analysis method for LVFX and CAM in wastewater by LC/MS/MS whose detection limits and recovery ratios are 2-3ng·l-1 and 53-87%, respectively. We also conducted algal growth inhibition tests using Pseudokirchneriella subcapitata, and results showed that the EC50s of LVFX and CAM are 1200μg·l-1 and 11μg·l-1, LOECs are 630μg·l-1 and 6.3μg·l-1, and NOECs are 310μg·l-1 and 3.1μg·l-1, respectively, LVFX and CAM concentrations in secondary effluent of five WWTPs that use the activated sludge process ranged from 152-323ng·l-1 and 303-567ng·l-1, respectively, which indicates that the PEC/PNEC ratio of LVFX is less than one but that of CAM exceeds two at the maximum secondary effluents if a safety factor of ten is considered. This suggests a possibility of algal growth inhibition due to CAM in WWTP discharge in the case of insufficient dilution of the receiving waters.
収録刊行物
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- 水環境学会誌
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水環境学会誌 27 (11), 707-714, 2004
公益社団法人 日本水環境学会
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詳細情報 詳細情報について
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- CRID
- 1390282680056742272
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- NII論文ID
- 10013786743
- 20000667386
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- NII書誌ID
- AN10372439
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- COI
- 1:CAS:528:DC%2BD2MXitFOntw%3D%3D
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- ISSN
- 18813690
- 09168958
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- NDL書誌ID
- 7149125
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- NDL
- Crossref
- CiNii Articles
- KAKEN
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- 抄録ライセンスフラグ
- 使用不可
