Biological Effects of Polycyclic Aromatic Hydrocarbon Derivatives

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  • BEKKI Kanae
    Division of Environmental Science and Engineering, Graduate School of Natural Science and Technology, Kanazawa University
  • TORIBA Akira
    Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
  • TANG Ning
    Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University Hyogo College of Medicine
  • KAMEDA Takayuki
    Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University
  • HAYAKAWA Kazuichi
    Faculty of Pharmaceutical Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University

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Other Title
  • 多環芳香族炭化水素誘導体が示す毒性作用

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Abstract

Polycyclic aromatic hydrocarbons (PAHs) are included in various environmental pollutants such as airborne particles and have been reported to induce a variety of toxic effects. On the other hand, PAH derivatives are generated from PAHs both through chemical reaction in the atmosphere and metabolism in the body.PAH derivatives have become known for their specific toxicities such as estrogenic/antiestrogenic activities and oxidative stress, and correlations between the toxicities and structures of PAH derivatives have been shown in recent studies. These studies are indispensable for demonstrating the health effects of PAH derivatives, since they would contribute to the comprehensive toxicity prediction of many kinds of PAH derivatives.

Journal

  • Journal of UOEH

    Journal of UOEH 35 (1), 17-24, 2013

    The University of Occupational and Environmental Health, Japan

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