Tumor Marker in Primary Lung Cancer

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  • SUGIO Kenji
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health
  • SUGAYA Masakazu
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health
  • HANAGIRI Takeshi
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health
  • YASUMOTO Kosei
    Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health

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Other Title
  • 肺癌の腫瘍マーカー
  • ハイガン ノ シュヨウ マーカー

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Description

Serum tumor markers are non-invasive diagnostic tools for malignant tumor and commonly used for screening of cancer and as an indicator of treatment-effect. In small cell lung cancer, NSE and proGRP are effective markers. In non-small cell lung cancer (NSCLC), CEA, SCC, CYFRA21-1, SLX and CA19-9 are commonly used for screening, and at least one marker among CEA, SCC or CYFRA21-1 is positive in 77% of patients with NSCLC. According to the histological type, the positive rate of CEA and CYFRA21-1 is high in adenocarcinoma patients, and the positive rate of CYFRA21-1 and SCC is high in squamous cell carcinoma patients. This review summarizes the clinical usefulness of tumor markers in primary lung cancer.

Journal

  • Journal of UOEH

    Journal of UOEH 26 (4), 473-479, 2004

    University of Occupational and Environmental Health, Japan

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