The Effects of Smoking on the Relationship Between Metabolic Syndrome and Arterial Stiffness
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- KIM Bu Kyung
- Department of Internal Medicine, Kosin University College of Medicine
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- WILSON Donald
- Department of Occupational Toxicology, Institute of Industrial Ecological Sciences, University of Occupational and Environmental Health, Japan.
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- CHOI Young Sik
- Department of Internal Medicine, Kosin University College of Medicine
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- PARK Yo-Han
- Department of Internal Medicine, Kosin University College of Medicine
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- PARK Eun-Kee
- Department of Medical Humanities and Social Medicine, Kosin University College of Medicine
Bibliographic Information
- Other Title
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- メタボリックシンドロームと動脈硬化の関連性への喫煙の影響
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Description
It has been reported that arterial stiffness assessed by pulse wave velocity (PWV) can predict cardiovascular morbidity and mortality. Metabolic syndrome and smoking are independently associated with increased risk of cardiovascular disease. The purpose of this study was to evaluate the effect of smoking on the relationship between metabolic syndrome and arterial stiffness. We retrospectively enrolled 1,530 men on whom brachial-ankle pulse wave velocity (baPWV) measurement had previously been performed as part of health screening at Kosin University Hospital. We found that PWV was positively correlated with the following variables: age (r=0.391, P<0.0001), systolic blood pressure (r=0.438, P<0.0001), diastolic blood pressure (r=0.377, P<0.0001), low-density lipoprotein (LDL) (r=0.068, P=0.008) and high-density lipoprotein (HDL) (r=0.027, P=0.287), whereas BMI was negatively correlated, although without statistical significance (r=-0.026, P=0.309). Among current smokers, PWV decreased with increasing BMI (from 1,387.9 to 1,311.6), and increased with increasing HDL (from 1,342.7 to 1,385.4). On the other hand, among never smokers, PWV increased with increasing BMI (from 1,382.3 to 1,458.8), and decreased with increasing HDL (from 1,391.2 to 1,369.7). PWV was inversely associated with BMI and HDL, and these differences are likely due to smoking.
Journal
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- Journal of UOEH
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Journal of UOEH 34 (2), 151-161, 2012
The University of Occupational and Environmental Health, Japan
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Details 詳細情報について
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- CRID
- 1390282680061164416
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- NII Article ID
- 130003359969
- 110009457181
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- NII Book ID
- AN0009832X
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- COI
- 1:STN:280:DC%2BC38jnvVyhuw%3D%3D
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- ISSN
- 21872864
- 0387821X
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- NDL BIB ID
- 023824265
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- PubMed
- 22768422
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- Text Lang
- en
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- Data Source
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- Abstract License Flag
- Disallowed