1. 凍結赤血球の自己血輸血への応用(平成9年度第43回低温生物工学会研究報告)

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  • 1. Frozen Autologous Transfusion Use in Elective Surgery(Papers presented at the 43rd Annual Meeting)
  • 凍結赤血球の自己血輸血への応用〔含 討論〕
  • トウケツ セッケッキュウ ノ ジコケツ ユケツ エ ノ オウヨウ ガン トウロ

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Autologous Blood (AB) transfusion is one of the most effective ways to avoid risks of homologous blood (HB) transfusion. Since the frozen red blood cells (RBCs) can be stored for a longer period, patients can predeposit the necessary amount of blood without their preoperative condition. We studied the frozen RBCs for AB transfusion use in elective surgery that performed from 1980 to 1996. A total of 1,355 patients undergoing surgical operation and participating in AB transfusion, which 699 cases for orthopedic surgery and 656 cases for cardiac surgery. From 90.7% (1,299/1,355) of patients were able to avoid HB transfusion. Patients who could avoid HB transfusion increased from 12.5% in 1980 to 100% in 1996 (p <0.05) and from 75.0% in 1987 to 89.6% in 1996 (p <0.05) in orthopedic surgery and cardiac surgery, respectively. No significant complications appeared during the donation periods and after retransfusion. Their average hemoglobin (Hb) level was remained above 11.0g/dl after one week of post-operative. We believe that the AB transfusion used in elective surgery is safe and effective, and its use should be widespread.

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