實驗的ぶるせら症に關する研究
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- 川名 林治
- 岩手醫科大學細菌學教室
書誌事項
- タイトル別名
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- Studies on Experimental Brucellosis
- II. Treatment of Experimental Brucellosis
- 第2篇-實驗的ぶるせら症の治療に關する研究
説明
Brucellosis has been one of those diseases, which are hardly amenable to medical treatment. Attempts have hitherto been made by many investigators for the treatment of the disease, without any satisfactory result. The author investigated the therapeutic effect of several medicaments on experimental brucellosis of mice, infected with Brucella abortus Bang. Penicillin, Streptomycin, Aureomycin, Chloromycetin, Terramycin, Ilotycin, Achromycin a-d immune serum were administered either individually or combined to the experimental animals, after the lapse of a certain period following the infection. The treatment was carried out with varying doses and combinations of medicaments and in different modes of administration. The animals were sacrificed in a certain period after the accomplishment of therapeutic plans, and their organs were examined for bacteria and histopathological findings.<BR>The results, summarized and compared in regard to the effect of applied therapeutic measures, indicated that a combined therapy with Aureomycin and Streptomycin was most effective, when they were administered for a long time by subcutaneous injection. The next effective was the combined therapy with Terramycin and Streptomycin. The therapeutic effect with these measures was then followed by that with Aureomycin, Terramycin and Ilotycin, given individually. Penicillin and the serum were ineffective, nor revealed Streptomycin, given singly, a definite therapeutic effect.<BR>The results of the investigation would suggest a new principle in the therapy of brucellosis.
収録刊行物
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- 日本傳染病學會雜誌
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日本傳染病學會雜誌 30 (6), 615-642, 1956
社団法人 日本感染症学会
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詳細情報 詳細情報について
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- CRID
- 1390282680071060992
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- NII論文ID
- 130004378776
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- ISSN
- 18845681
- 00214817
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可