Anemia is an Independent Predictor of Long-Term Adverse Outcomes in Patients Hospitalized With Heart Failure in Japan A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
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- Hamaguchi Sanae
- Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine
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- Tsuchihashi-Makaya Miyuki
- Department of Clinical Research and Informatics, Research Institute, International Medical Center of Japan
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- Kinugawa Shintaro
- Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine
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- Yokota Takashi
- Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine
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- Takeshita Akira
- Futsukaichi Saiseikai Hospital
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- Yokoshiki Hisashi
- Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine
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- Tsutsui Hiroyuki
- Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine
書誌事項
- タイトル別名
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- A Report From the Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD)
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説明
Background: Anemia is common in patients with heart failure (HF) and is associated with worse outcomes. However, the effects of anemia are unknown in an unselected group of HF patients encountered in routine clinical practice in Japan. The impact of anemia on long-term outcomes including mortality and rehospitalization among patients hospitalized with HF was thus assessed. Methods and Results: The Japanese Cardiac Registry of Heart Failure in Cardiology (JCARE-CARD) prospectively studied the characteristics and treatments in a broad sample of patients hospitalized with worsening HF and the outcomes were followed. Study cohorts (n=1,960) were classified into 4 groups by discharge hemoglobin quartiles: <10.1 g/dl (n=482), 10.1-11.9 g/dl (n=479), 12.0-13.6 g/dl (n=487), and ≥13.7 g/dl (n=512). Of the total cohort of HF patients, 57% had anemia, defined by using the World Health Organization definition. Patients with lower hemoglobin quartiles had higher rates of all-cause death, cardiac death, and rehospitalization due to worsening HF. After multivariable adjustment, the risk for all-cause death, cardiac death, and rehospitalization significantly increased with low hemoglobin concentrations. Conclusions: Anemia was quite common especially in patients with HF encountered in routine clinical practice in Japan, and lower hemoglobin was independently associated with long-term adverse outcomes in these patients. (Circ J 2009; 73: 1901-1908)<br>
収録刊行物
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- Circulation Journal
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Circulation Journal 73 (10), 1901-1908, 2009
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390282680079228032
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- NII論文ID
- 10025936236
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- NII書誌ID
- AA11591968
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- COI
- 1:STN:280:DC%2BD1MnksFKksA%3D%3D
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- ISSN
- 13474820
- 13469843
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- PubMed
- 19652398
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- 本文言語コード
- en
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- 資料種別
- journal article
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- データソース種別
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- JaLC
- Crossref
- PubMed
- CiNii Articles
- OpenAIRE
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