Cell-Based Therapies for Ischemic Heart Disease "Trick and Treat"

DOI Web Site 4 Citations 70 References
  • Limbourg Anne
    Junior Research Group Regenerative Agents, Excellence Cluster Rebirth Integriertes Forschungs- und Behandlungszentrum (IFB-Tx) Department of Cardiology, Hannover Medical School
  • Limbourg Florian
    Junior Research Group Regenerative Agents, Excellence Cluster Rebirth Department of Cardiology, Hannover Medical School
  • Drexler Helmut
    Junior Research Group Regenerative Agents, Excellence Cluster Rebirth Integriertes Forschungs- und Behandlungszentrum (IFB-Tx) Department of Cardiology, Hannover Medical School

Bibliographic Information

Other Title
  • "Trick and Treat"

Search this article

Description

Cell therapy is a promising approach to improve cardiac function in patients with ischemic heart disease. Beneficial effects of cell therapy have been shown in experimental studies and clinical trials. However, with current treatment strategies the therapeutic effect is limited. In the current article, critical aspects of cell therapy are discussed: cell type, the state of ischemic heart disease and the condition of cells at the time of treatment. Because treatment options of native cells by systemic pharmacotherapy are limited, we propose a concept of ex vivo preconditioning to overcome functional cell impairment and to enhance cell-based regenerative approaches. (Circ J 2009; 73: 2179-2182)<br>

Journal

  • Circulation Journal

    Circulation Journal 73 (12), 2179-2182, 2009

    The Japanese Circulation Society

Citations (4)*help

See more

References(70)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top