Determinants and Long-Term Outcomes of Percutaneous Coronary Interventions vs. Surgery for Multivessel Disease According to Clinical Presentation
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- Hong Sung-Jin
- Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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- Kim Byeong-Keuk
- Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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- Shin Sanghoon
- Division of Cardiology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital
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- Suh Yongsung
- Division of Cardiology, Department of Internal Medicine, Myongji Hospital
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- Kim Seunghwan
- Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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- Ahn Chul-Min
- Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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- Kim Jung-Sun
- Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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- Ko Young-Guk
- Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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- Choi Donghoon
- Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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- Hong Myeong-Ki
- Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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- Jang Yangsoo
- Division of Cardiology, Severance Cardiovascular Hospital, Yonsei University College of Medicine
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<p>Background:The long-term outcome of percutaneous coronary intervention (PCI) vs. coronary artery bypass graft (CABG), particularly for patients with non-ST-elevation acute coronary syndrome (NSTE-ACS), remains controversial.</p><p>Methods and Results:We retrospectively analyzed 2,827 patients (stable coronary artery disease [SCAD], n=1,601; NSTE-ACS, n=1,226) who underwent either PCI (n=1,732) or CABG (n=1,095). The 8-year composite of cardiac death and myocardial infarction (MI) was compared between PCI and CABG before and after propensity matching. For patients with NSTE-ACS, PCI was performed more frequently for those with higher Thrombolysis in Myocardial Infarction risk score and 3-vessel disease, and PCI led to significantly higher 8-year composite of cardiac death and MI than CABG (14.1% vs. 5.9%, hazard ratio [HR]=2.22, 95% confidence interval [CI]=1.37–3.58, P=0.001). There was a significant interaction between clinical presentation and revascularization strategy (P-interaction=0.001). However, after matching, the benefit of CABG vs. PCI was attenuated in patients with NSTE-ACS, whereas it was pronounced in those with SCAD. Interactions between clinical presentation and revascularization strategy were not observed (P-interaction=0.574).</p><p>Conclusions:Although the determinants of PCI vs. CABG in real-world clinical practice differ according to the clinical presentation, a significant interaction between clinical presentation and revascularization strategy was not noted for long-term outcomes. The revascularization strategy for patients with NSTE-ACS can be based on the criteria applied to patients with SCAD.</p>
収録刊行物
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- Circulation Journal
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Circulation Journal 82 (4), 1092-1100, 2018
一般社団法人 日本循環器学会
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詳細情報 詳細情報について
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- CRID
- 1390282680083204352
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- NII論文ID
- 130006528565
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- NII書誌ID
- AA11591968
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- ISSN
- 13474820
- 13469843
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- NDL書誌ID
- 028895504
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- PubMed
- 29434090
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可