- 【Updated on May 12, 2025】 Integration of CiNii Dissertations and CiNii Books into CiNii Research
- Trial version of CiNii Research Knowledge Graph Search feature is available on CiNii Labs
- 【Updated on June 30, 2025】Suspension and deletion of data provided by Nikkei BP
- Regarding the recording of “Research Data” and “Evidence Data”
Carbon Monoxide-Induced Cardiomyopathy
-
- Jung Yoon-seok
- Department of Emergency Medicine, Ajou University School of Medicine
-
- Lee Ji-sook
- Department of Emergency Medicine, Ajou University School of Medicine
-
- Min Young-gi
- Department of Emergency Medicine, Ajou University School of Medicine
-
- Park Jin-sun
- Department of Cardiology, Ajou University School of Medicine
-
- Jeon Woo-chan
- Department of Emergency Medicine, Ilsan Inje Paik Hospital
-
- Park Eun-jung
- Department of Emergency Medicine, Ajou University School of Medicine
-
- Shin Joon-han
- Department of Cardiology, Ajou University School of Medicine
-
- Oh Sungho
- Daegu Research Center for Medical Device and Green Energy, Korea Institute of Machinery & Materials
-
- Choi Sang-Cheon
- Department of Emergency Medicine, Ajou University School of Medicine
Bibliographic Information
- Other Title
-
- Carbon Monoxide-Induced Cardiomyopathy : Epidemiology, Clinical Characteristics and Prognosis
- – Epidemiology, Clinical Characteristics and Prognosis –
Search this article
Description
Background: Previous reports demonstrated mechanisms of cardiac toxicity in acute carbon monoxide (CO) poisoning. Still, none established CO-induced cardiomyopathy (CMP) as a clinical entity. The aim of this study is to investigate CO-induced CMP in patients with acute CO poisoning in terms of its epidemiology, clinical characteristics, and prognosis. Methods and Results: A retrospective study was conducted on consecutive patients who were diagnosed with acute CO poisoning at the emergency department of Ajou University Hospital during the period of 62 month. Six hundred and twenty-six patients were diagnosed with acute CO poisoning. During the initial echocardiography, 19 patients were abnormal: (1) global hypokinesia/akinesia (n=7), (2) regional wall hypokinesia/akinesia [n=12; takotsubo type (n=6), reverse takotsubo type (n=2), non-specific type (n=4)]. The ejection fraction (EF) was 36.3±13.5% (from 15% to 55%) and less than 45% for 14 patients. In the follow-up echocardiography performed within 12 days after the initial performance, most patients were found to have cardiac wall motion abnormalities, and their EF had returned to normal (ie, EF ≥50%). Conclusions: CO-induced CMP was identified in 3.04% (n=19) of all patients (n=626). It might not be too critical in acute clinical courses of acute CO poisoning because the prognosis seems favorable. Considering the common factors between CO-induced CMP and takotsubo CMP, myocardial stunning subject to a catecholamine surge most likely plays a central role in the development of CO-induced CMP. (Circ J 2014; 78: 1437–1444)<br>
Journal
-
- Circulation Journal
-
Circulation Journal 78 (6), 1437-1444, 2014
The Japanese Circulation Society
- Tweet