The Who, What, Why, When, How and Where of Vasospastic Angina
-
- Beltrame John F.
- The Queen Elizabeth Hospital Discipline of Medicine, University of Adelaide, Central Adelaide Local Health Network
-
- Crea Filippo
- Institute of Cardiology, Catholic University of the Sacred Heart
-
- Kaski Juan Carlos
- Cardiovascular and Cell Sciences Research Institute, St George’s, University of London
-
- Ogawa Hisao
- Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University
-
- Ong Peter
- Department of Cardiology, Robert-Bosch-Krankenhaus
-
- Sechtem Udo
- Department of Cardiology, Robert-Bosch-Krankenhaus
-
- Shimokawa Hiroaki
- Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
-
- Bairey Merz C. Noel
- Barbra Streisand Women’s Heart Center, Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center
Search this article
Abstract
Ischemic heart disease involves both “structural” and/or “functional” disorders of the coronary circulation. Structural atherosclerotic coronary artery disease (CAD) is well recognized, with established diagnostic and treatment strategies. In contrast, “functional CAD” has received limited attention and is seldom actively pursued in the investigation of ischemic heart disease. Vasospastic angina encompasses “functional CAD” attributable to coronary artery spasm and this “state of the art” consensus statement reviews contemporary aspects of this disorder. Patients with vasospastic angina typically present with angina at rest that promptly responds to short-acting nitrates and is associated with transient ischemic ECG changes. Although spontaneous episodes may be documented, provocative spasm testing may be required to confirm the diagnosis. It is important to diagnose vasospastic angina because it may be associated with major adverse events that can be prevented with the use of appropriate vasodilator therapy (eg, calcium-channel blockers) and the avoidance of aggravating stimuli (eg, smoking). Future studies are required to clarify the underlying pathophysiology, natural history and effective treatments for patients refractory to conventional therapy. (Circ J 2016; 80: 289–298)
Journal
-
- Circulation Journal
-
Circulation Journal 80 (2), 289-298, 2016
The Japanese Circulation Society
- Tweet
Keywords
Details 詳細情報について
-
- CRID
- 1390282680085250688
-
- NII Article ID
- 130005120904
-
- NII Book ID
- AA11591968
-
- ISSN
- 13474820
- 13469843
-
- NDL BIB ID
- 027054303
-
- PubMed
- 26686994
-
- Text Lang
- en
-
- Data Source
-
- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
-
- Abstract License Flag
- Disallowed