Comparison of Cardiovascular Mortality in the Great East Japan and the Great Hanshin-Awaji Earthquakes　– A Large-Scale Data Analysis of Death Certificates –

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  • Takegami Misa
    Department of Preventive Medicine and Epidemiologic Informatics, National Cerebral and Cardiovascular Center
  • Miyamoto Yoshihiro
    Department of Preventive Medicine and Epidemiologic Informatics, National Cerebral and Cardiovascular Center
  • Yasuda Satoshi
    Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center
  • Nakai Michikazu
    Department of Preventive Medicine and Epidemiologic Informatics, National Cerebral and Cardiovascular Center
  • Nishimura Kunihiro
    Department of Preventive Medicine and Epidemiologic Informatics, National Cerebral and Cardiovascular Center
  • Ogawa Hisao
    National Cerebral and Cardiovascular Center
  • Hirata Ken-ichi
    Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine
  • Toh Ryuji
    Division of Evidence-based Laboratory Medicine, Kobe University Graduate School of Medicine
  • Morino Yoshihiro
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University School of Medicine
  • Nakamura Motoyuki
    Division of Cardiology, Department of Internal Medicine, Iwate Medical University School of Medicine
  • Takeishi Yasuchika
    Department of Cardiology and Hematology, Fukushima Medical University
  • Shimokawa Hiroaki
    Department of Cardiovascular Medicine, Tohoku University Graduate School of Medicine
  • Naito Hiroaki
    National Cerebral and Cardiovascular Center

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Other Title
  • LATE BREAKING COHORT STUDY (JCS 2015) : Comparison of Cardiovascular Mortality in the Great East Japan and the Great Hanshin-Awaji Earthquakes : A Large-Scale Data Analysis of Death Certificates
  • Comparison of cardiovascular mortality in the Great East Japan and the Great Hanshin-Awaji Earthquakes—a large-scale data analysis of death certificates

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Background:Large earthquakes have been associated with cardiovascular disease (CVD) mortality. In Japan, the 1995 Great Hanshin-Awaji (H-A) Earthquake was an urban-underground-type earthquake, whereas the 2011 Great East Japan (GEJ) Earthquake was an ocean-trench type. In the present study, we examined how these different earthquake types affected CVD mortality.Methods and Results:We examined death certificate data from 2008 to 2012 for 131 municipalities in Iwate, Miyagi, and Fukushima prefectures (n=320,348) and from 1992 to 1996 for 220 municipalities in Hyogo, Osaka, and Kyoto prefectures (n=592,670). A Poisson regression model showed significant increases in the monthly numbers of acute myocardial infarction (AMI)-related deaths (incident rate ratio [IRR] GEJ=1.34, P=0.001; IRR of H-A=1.57, P<0.001) and stroke-related deaths (IRR of GEJ=1.42, P<0.001; IRR of H-A=1.33, P<0.001) after the earthquakes. Two months after the earthquakes, AMI deaths remained significant only for H-A (IRR=1.13, P=0.029). When analyzing the standardized mortality ratio (SMR) after the earthquakes using the Cochran-Armitage trend test, seismic intensity was significantly associated with AMI mortality for 2 weeks after both the GEJ (P for trend=0.089) and H-A earthquakes (P for trend=0.005).Conclusions:Following the GEJ and H-A earthquakes, there was a sharp increase in CVD mortality. The effect of the disaster was sustained for months after the H-A earthquake, but was diminished after the GEJ Earthquake. (Circ J 2015; 79: 1000–1008)

Journal

  • Circulation Journal

    Circulation Journal 79 (5), 1000-1008, 2015

    The Japanese Circulation Society

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