Activation of Adrenergic β Receptor by Free FattyAcid Composition

DOI Web Site Web Site 7 References
  • NAKANO Yuka
    Department of Chemistry, Rikkyo Univerisy, 3-34-1 Nishi-Ikebukuro, Toshima, Tokyo 171-8501 Japan
  • KAWASE Saki
    Department of Chemistry, Rikkyo Univerisy, 3-34-1 Nishi-Ikebukuro, Toshima, Tokyo 171-8501 Japan
  • SANDOU Ayumi
    Department of Chemistry, Rikkyo Univerisy, 3-34-1 Nishi-Ikebukuro, Toshima, Tokyo 171-8501 Japan
  • TOKIWA Hiroaki
    Department of Chemistry, Rikkyo Univerisy, 3-34-1 Nishi-Ikebukuro, Toshima, Tokyo 171-8501 Japan

Bibliographic Information

Other Title
  • 遊離脂肪酸混合物による β アドレナリン受容体の活性化
  • ユウリ シボウサン コンゴウブツ ニ ヨル vアドレナリン ジュヨウタイ ノ カッセイカ

Search this article

Abstract

We report the novel molecular mechanism of activation of the adrenergic β receptor by free fatty acid composition based on the activated experimental structure of the receptor. Dimers of adrenergic β receptors have been stably formed due to sandwich structure between cholesterols and free fatty acids. Stabilization of the dimer formation enhanced signal communication initiated by the ligand binding.

Journal

References(7)*help

See more

Related Projects

See more

Keywords

Details 詳細情報について

Report a problem

Back to top