A Case of Squamous Cell Carcinoma Arising from Chronic Discoid Lupus Erythematosus

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  • 慢性円板状エリテマトーデスの皮疹上に生じた有棘細胞癌

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Description

A 70-year-old male patient developed erythema on the dorsum of his nose at the age of about 35 years. Then, similar erythema gradually appeared on the many sites of the body. The skin lesion was diagnosed as chronic discoid lupus erythematosus in another hospital. At the age of 43 years, a tumor developed on the erythema of the left upper limb. The tumor was resected and diagnosed as SCC. Later, squamous cell carcinoma and keratoacanthoma developed on the lower lip, neck and left upper limb and were resected. At the age of 51 years, a tumor appeared on te right side of his neck, and was histologically diagnosed as squamous cell carcinoma and malignant hemangioendothelioma. The patient underwent resection and treatment with DTIC (dimethyltriazenoimidazole carboxamide) was done. At the age of 65 years, squamous cell carcinoma developed on the left retroauricular region. Both tumors were resected in another hospital. On July 15, 1999, the patient was referred to our hospital because of the change of his residence. At the end of January, 2000, the patient exhibited a small nodule and shallow ulcer on the cicatricial lesion of DLE on the nape, and the nodule and ulcer were slowly enlarged. The lesion was histologically diagnosed as squamous cell carcinoma by skin biopsy. On July 11, 2000, resection of the tumor and skin grafting were performed. At present, about one year after the surgery, the patient has neither recurrence nor metastasis of SCC.

Journal

  • Hifu no kagaku

    Hifu no kagaku 1 (2), 118-122, 2002

    Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association

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