Safety Study of Acne Treatment Cosmetics for Females with Facial Acne Vulgaris

DOI
  • Tanioka Miki
    Department of Dermatology, Kyoto University Graduate School of Medicine
  • Aiba Setsuya
    Department of Dermatology, Tohoku University Graduate School of Medicine
  • Kikuchi Katsuko
    Department of Dermatology, Tohoku University Graduate School of Medicine
  • Ishikawa Osamu
    Department of Dermatology, Gunma University, Postgraduate School of Medicine
  • Nagai Yayoi
    Department of Dermatology, Gunma University, Postgraduate School of Medicine
  • Terui Tadashi
    Department of Dermatology, Nihon University, School of Medicine
  • Shimizu Hidenao
    Department of Dermatology, Nihon University, School of Medicine
  • Ito Masatoshi
    First Department of Dermatology, Toho University Graduate School of Medicine
  • Kantoh Hiromi
    First Department of Dermatology, Toho University Graduate School of Medicine
  • Matsunaga Kayoko
    Department of Dermatology, Fujita Health University Graduate School of Medicine
  • Yagami Akiko
    Department of Dermatology, Fujita Health University Graduate School of Medicine
  • Katayama Ichiro
    Department of Dermatology, Graduate School of Medicine Osaka University
  • Inui Shigeki
    Department of Dermatology, Graduate School of Medicine Osaka University
  • Ishii Masamitsu
    Department of Dermatology, Osaka City University Graduate School of Medicine
  • Kobayashi Hiromi
    Department of Dermatology, Osaka City University Graduate School of Medicine
  • Kato Atsuko
    Department of Dermatology, Osaka Kaisei Hospital
  • Furue Masutaka
    Department of Dermatology, Kyushu University Graduate School of Medicine
  • Fukiwake Noriko
    Department of Dermatology, Kyushu University Graduate School of Medicine
  • Imayama Syuhei
    Imayama Syuhei Clinic&Labo
  • Suzuki Yumiko
    Scientific Research Department, Quality Assurance Center, Shiseido Co., Ltd.
  • Miyachi Yoshiki
    Department of Dermatology, Kyoto University Graduate School of Medicine

Bibliographic Information

Other Title
  • 尋常性ざ瘡患者を対象としたざ瘡用化粧品(医薬部外品)の使用試験

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Description

We carried out a four-week study in patients with facial acne vulgaris in order to assess the safety of new acne treatment cosmetics (a cream and a lotion) containing sulfur and dipotassium glycyrrhizate. We found adverse skin reaction in 5.2% of the subjects who used the acne treatment cream, and in 6.1% of the subjects who used the acne treatment lotion. These adverse skin reactions were slight or moderate, and there was no severe reaction. The average number of acne eruptions at 4 weeks was significantly decreased after application, compared with baseline. The satisfaction index for skin condition, obtained by using a visual analog scale, was improved after the study. The results indicate that the acne treatment cream and lotion are safe and useful for patients with acne.

Journal

  • Hifu no kagaku

    Hifu no kagaku 7 (3), 354-363, 2008

    Meeting of Osaka Dermatological Association/Meeting of Keiji Dermatological Association

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